Research is an integral part of our philosophy at Klorane Laboratories. As far as dermo-cosmetic products are concerned, Klorane research has always conducted evaluations in compliance with the regulations in force and in accordance with Pierre Fabre Laboratories’ own code of ethics. These evaluations answer our concern for consumer safety, and substantiate our claims of efficacy. Our main research activities are outlined below:
Research on plant-derived active substances:
New plant active substances are sought out by the Phytochemistry department in collaboration with the Pierre Fabre group’s Natural Substances Research Centre. This joint effort makes it possible to fully research plants of interest. The Phytochemistry department answers to a substructure of the Phytofilière®. This makes it possible for Klorane Laboratories to select the most appropriate plant for the desired action.
Different tests are carried out on Klorane products.
- Evaluation of safety
Klorane Laboratories abide by the fundamental precept of the pharmaceutical industry: “Primum non nocere”, a Latin phrase meaning “First, do no harm”. It is out of respect for this golden rule that no test is begun without the go-ahead of the toxicologist. The toxicologist evaluates the innocuousness of the product, in other words whether it is capable of causing harm. After studying the file received from the product safety cell, the toxicologist delivers the visa attesting to the product’s safety. The other tests can then begin.
- Animal testing
Our products are not tested on animals.
- Sensory analysis
In this laboratory, a panel of 70 trained people measure the sensations perceived upon product application. These tests are performed blind and in comparison with other products. The standard descriptors, such as ease of application and skin shine, suppleness and softness, are statistically noted. The result is an objective profile of the tested product, which will serve as a guide for the cosmetic chemist in his search for the ideal product.
- Usage tests
These are tests conducted in real-life conditions on target populations of habitual users of the type of product to be tested. 70 to 100 untrained people receive the product to be tested at their home in their normal conditions of use. The results of these tests reflect their appreciation of pleasure of use and product efficacy. It is possible for a product to be reformulated as a result of such a test.
- Tolerability in humans
The product is first tested on healthy skin then, according to the type of product and its claims, on undamaged skin. It may be applied just once or repeatedly according to specific methodologies. These methodologies vary according to the type of product, the type of skin type (requirements for use on babies’ skin are particularly strict), and the site of application.
- Biometric study
The purpose of this study is to evaluate the efficacy of products by objectively measuring very specific parameters: hair elasticity, skin moisture levels, etc. These studies are performed in collaboration with the skin research centre Hôtel Dieu Saint-Jacques, in Toulouse.
Sun products constitute an important part of our business: the evaluation of protection factors to ensure satisfactory UVA and UVB protection, resistance to water, cosmetic appeal, clinical studies evaluating their efficacy in extreme conditions (sea, mountains, tropical climates, etc.) and in the prevention of certain sun-induced pathologies.
- Efficacy studies
Study protocols are drawn up by the clinical research department in partnership with doctors and specialist consultants. These clinical studies are conducted to prove the efficacy of a product on its target population. This type of study is of particular interest in the case of anti-hair loss products.